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Background: SARS-CoV-2 infection has been declared as pandemic by the WHO. There is strong epidemiological evidence that viruses during pregnancy increase the risk of severity and mortality. CDC has published that pregnant woman infected with COVID-19 are at risk of severe illness, complications and death. Currently there is not enough evidence on vertical transmission due to limited data.
Objective: The present study was conducted to evaluate the foetal and maternal outcome in COVID-19 infected pregnant women at our institution.
Materials and methods: Pregnant women presenting to the institution with symptoms of COVID-19 were enrolled in this study during the period from May 2020 to May 2021. They were followed till delivery. The foetal and maternal outcomes were evaluated.
Results: We included 40 pregnant women, of which 15 did not deliver. Twenty-five pregnant women delivered. The mean age of women was 25.7 ± 2.88 years. Fever, cough, sore throat and shortness of breath were the commonest presenting symptoms. Majority of the women in third trimester (82.5%) had COVID-19 infection. Equal prevalence of lower segment caesarean section and normal vaginal delivery was seen. Maternal mortality rate was 7.5%. There were in all 4 (16%) neonatal deaths. One (4.8%) neonate was found to be COVID-19 positive.
Conclusion: COVID-19 infection had an adverse impact on both the maternal and neonatal outcome, with vertical transmission seen in one neonate. Third trimester of pregnancy was most affected by Covid-19 infection. All the pregnant women with COVID-19 should be well informed about the adverse impact of this virus on maternal and neonatal outcome.
Keywords: COVID-19; Infection in pregnancy; Virus; SARS-CoV-2 infection