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We reported a case of young female patient with short stature and secondary amenorrhoea with bilateral multiple large ovarian cysts. A 15-year old girl presented with pelvic and abdominal pain associated with abdominal distension since three months and severe asthenia. Her menarche was 10 months before presentation, since then she was amenorrhoeic. On examination patient had large vague abdominal lump of 20x20cm. Imaging revealed, bilateral large multiseptated, multicystic ovarian masses (Volume: Right. ovary 548cc and Left ovary 320cc). Laboratory findings were a surprise and showed severe hypothyroidism (thyroid-stimulating hormone [TSH]: > 1000 mIU/L), mild anaemia, and hyperprolactinemia (131ng/ml). USG thyroid and MRI brain was done, showing normal thyroid and pituitary. Tumour markers were normal. As soon as thyroid replacement therapy was initiated, ovarian cysts started vanishing and all symptoms progressively disappeared, biochemical and hormonal values normalized, and she started to have regular menstrual cycles, thereby improving the condition of the patient significantly. This case report highlights the rare and often missed association between hypothyroidism and ovarian cysts.
Keywords: Ovarian cysts; Secondary amenorrhoea; Hypothyroidism; Thyroxine