GOODPASTURE'S SYNDROME WITH p-ANCA VASCULITIS IN PREGNANCY

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Dr. Anuradha Tibrewal
Dr. Prawash Kumar Chowdhary

Abstract

Goodpasture's syndrome (GPS) associated with perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA) vasculitis complicating pregnancy is extremely rare. We report a case of 29-year-old multipara (G2P1L1 with previous vaginal delivery) who presented at sixteenthweek of pregnancy with low grade fever for seven days associated with acute haemoptysis and shortness of breath. The patient had generalised oedema and decrease in urine output. The case was diagnosed to have rapidly progressive glomerulonephritis. The patient underwent spontaneous termination of pregnancy. Steroids and cytotoxic drugs were started along with plasma exchange and haemodialysis. Despite aggressive management she remained dialysis dependent and adviced for future renal transplantation.



Keywords: p-ANCA; Haemodialysis; Dialysis; Renal Transplant

Published Jul 26, 2020

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