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Objective: Abnormal uterine bleeding (AUB) is common gynaecological problem in women of reproductive age group. Its prevalence is approximately 19% in reproductive age women. The present study was aimed to evaluate the role of transvaginal ultrasonography and colour Doppler in diagnosing uterine pathologies and later its confirmation by histopathology.
Materials & Methods: Sixty women presenting with complaint of abnormal uterine bleeding between the age group of 30-60 years were included in the study. Transvaginal ultrasound (TVS) & colour Doppler (CD) was done followed by dilatation and curettage (in premenustral phase in case of premenopausal women) in all cases and histopathological examination of tissue and specimen obtained after surgery was done in selected cases. Uterine size, endometrial thickness and blood flow indices were measured. Statistical analysis of data was done using ANOVAand Chi-square test.
Results: Colour Doppler transvaginal ultrasonography (CDTU) showed abnormal studies in 39 patients (65%), D&C and tissue specimen obtained after surgery revealed abnormalities in 38 patients (63.3%). Thus CDTU has sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) of 100%, 95.5%, 97.4%, 100% respectively. In abnormal CDTU finding, only 1.7% cases had normal histopathological examination (HPE). CDTU effectively diagnosed all malignant and potentially malignant states.
Conclusion: CDTU can be used as a screening tool for malignancy. It is better than TVS for screening endometrial pathology which can be confirmed by D&C.
Keywords: AUB; CDTU; Endometrial thickness; Endometrial pathology; Histopathological examination