Unusual Case of Gliosarcoma: Dilemma & Challenges in its Management

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Dr. Anupama Dave
Dr. Neha Reddy
Dr. Amrita Tripathy
Dr. Deepandra Verma


Primary malignant brain tumour in a pregnant patient is an extremely rare scenario and equally fatal standing as a fifth leading cause of cancer death in age group 20-39 years, which is a reproductive age group. A 23 years old female with 35 weeks singleton pregnancy presented to OPD with blurring of vision and headache, with a prior history of brain tumour and a MRI suggestive of recurrence of tumour with infarcts in post cerebral area. Patient managed to deliver with, a multidisciplinary team of obstetrician, neonatologist, anesthetist, neurologist revealed grade IV gliosarcoma on histopathology. Further the patient was transferred for chemoradiation with regular follow up.

Gliosarcoma represents a rare entity and being uncommon they pose a great challenge for the obstetricians and need their case reporting, discussions and preparedness. Management needs decisions balancing maternal versus foetal risks. An intense need for regular follow up with MRI specially during pregnancy where they progress rapidly.

Keywords: Brain Tumour; Chemoradiation; Gliosarcoma

Published May 22, 2020

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