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Cervical cancer is the most common gynaecological malignancy worldwide. The most common type of cervical carcinoma is squamous cell carcinoma followed by adenocarcinoma. Adenocarcinoma of cervix is further categorized histologically into clear cell, mucinous, endometrioid, serous and mesonephric subtypes. Primary clear cell adenocarcinoma of cervix is a rare neoplastic entity, accounting only 4% of all cervical adenocarcinomas. It occurs in young women exposed to diethylstilbestrol (DES) in utero and is extremely rare in women without in utero DES exposure where it concerns mostly postmenopausal women.
Here we report a rare case of primary clear cell adenocarcinoma of cervix in a 30 year old Asian woman who presented with primary infertility, without history of in-utero DES exposure.
Through this case, authors would like to highlight the probability of rare occurrence of such a cancer and management of cervical adenocarcinoma in a young woman through review of the available literature.
Keywords: Adenocarcinoma; Cervix; Clear cell adenocarcinoma